Prosecution Insights
Last updated: August 18, 2026

The Brigham And Women`S Hospital Inc.

9 pending office actions • 9 art units • 9 examiners • 0 of 9 (0%) have an AI response strategy ready • 7 patents granted in the last 365 days

Portfolio Summary

9
Total Pending OAs
5
Non-Final OAs
4
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 5 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
1
Due this month
0
Due in next 60 days
1
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 5 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)Due ≤ 30 days (1)Due later (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

4
Hard (44%)
4
Medium (44%)
1
Easy (11%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (22%)
§103 only4 (44%)
§112 only1 (11%)
Multi-statute (no §101)2 (22%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

9
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

90 h
Manual time on pending OAs
18 h
Time saved (low, 20%)
31 h
Time saved (mid, 35%)
0.8 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
WILLIAMS, EMMALEE RAE 1 0.0% +0.0%
SHIAO, REI TSANG 1 79.8% -33.7%
NGUYEN, NAM P 1 54.7% +47.4%
LEE, SIN J 1 68.9% +25.5%
WANG, RUIXUE 1 57.4% +22.1%
MARCSISIN, ELLEN JEAN 1 34.0% +50.2%
MAHLUM, JONATHAN DAVIS 1 51.5% +20.8%
WU, JULIE ZHEN QIN 1 61.6% +52.1%
TRAN, CHRISTINA L 1 48.2% +45.5%

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
17698617 METHODS OF SUPPRESSING MICROGLIAL ACTIVATION WU, JULIE ZHEN QIN 22d
18477970 LONG-TERM STABILIZATION, FORMULATION AND TABLETING OF LIVE MICROBIAL CELLS WILLIAMS, EMMALEE RAE
18268034 BLOOD-BASED PROTEIN BIOMARKER PANEL FOR EARLY AND ACCURATE DETECTION OF CANCER NGUYEN, NAM P
18038392 LONG-ACTING AND LONG-CIRCULATING DELIVERY VEHICLES LEE, SIN J

Interview Candidates (7)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 7 ordered by deadline are shown.

App #TitleExaminerDue in
17284919 The long non-coding RNA INCA1 and Homo sapiens heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1) as therapeutic targets for immunotherapy TRAN, CHRISTINA L 37d overdue
18014947 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Peptide Epitopes WANG, RUIXUE 19d overdue
18012111 Single Molecule Assays for Ultrasensitive Detection of Biomolecules MARCSISIN, ELLEN JEAN 8d overdue
17698617 METHODS OF SUPPRESSING MICROGLIAL ACTIVATION WU, JULIE ZHEN QIN 22d
18268034 BLOOD-BASED PROTEIN BIOMARKER PANEL FOR EARLY AND ACCURATE DETECTION OF CANCER NGUYEN, NAM P
18038392 LONG-ACTING AND LONG-CIRCULATING DELIVERY VEHICLES LEE, SIN J
17766945 Activators of Heme Regulated Inhibitor Kinase (HRI) MAHLUM, JONATHAN DAVIS

Top Art Units

Art UnitApps
1653 1
1691 1
1678 1
1613 1
1672 1
1677 1
1625 1
1644 1
1637 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18477970 LONG-TERM STABILIZATION, FORMULATION AND TABLETING OF LIVE MICROBIAL CELLS WILLIAMS, EMMALEE RAE 1653 §101§102§103§112 Non-Final OA Pending Sep 29, 2023
18278078 INHIBITORS OF EPHB3 SIGNALING SHIAO, REI TSANG 1691 §103 Final Rejection 70d Pending Aug 21, 2023
18268034 BLOOD-BASED PROTEIN BIOMARKER PANEL FOR EARLY AND ACCURATE DETECTION OF CANCER NGUYEN, NAM P 1678 §101§102§112 Non-Final OA Pending Jun 16, 2023
18038392 LONG-ACTING AND LONG-CIRCULATING DELIVERY VEHICLES LEE, SIN J 1613 §102§112 Non-Final OA Pending May 23, 2023
18014947 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Peptide Epitopes WANG, RUIXUE 1672 §103 Non-Final OA 19d overdue Pending Jan 06, 2023
18012111 Single Molecule Assays for Ultrasensitive Detection of Biomolecules MARCSISIN, ELLEN JEAN 1677 §103Other Final Rejection 8d overdue Pending Dec 21, 2022
17766945 Activators of Heme Regulated Inhibitor Kinase (HRI) MAHLUM, JONATHAN DAVIS 1625 §103 Final Rejection Pending Apr 06, 2022
17698617 METHODS OF SUPPRESSING MICROGLIAL ACTIVATION WU, JULIE ZHEN QIN 1644 §103§112 Non-Final OA 22d Pending Mar 18, 2022
17284919 The long non-coding RNA INCA1 and Homo sapiens heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1) as therapeutic targets for immunotherapy TRAN, CHRISTINA L 1637 §112 Final Rejection 37d overdue Pending Apr 13, 2021

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